Dr. Alice Dodgson is an oncologist whose experiments with an unapproved drug have just cost a patient his life. Summoned to Jamaica by an affluent American, Dr. Dodgson is assigned the duty of caring for his cancer-stricken brother, Wesley. Though Dr. Dodgson at first dismisses the local tales of zombies and possession, her growing feelings for her patient soon bring her to understand the powerful curse of a local witch doctor.